CAMBRIDGE, Mass. and BEIJING, China, Feb. 05, 2018 — BeiGene, Ltd. (NASDAQ:BGNE), a commercial-stage biopharmaceutical company focused on developing and commercializing innovative molecularly targeted and immuno-oncology drugs for the treatment of cancer, announced that it will present preliminary Phase I data on its investigational anti-PD-1 antibody, tislelizumab, in urothelial carcinoma (bladder cancer) at the upcoming 2018 Genitourinary Cancers Symposium, to be held February 8-10 in San Francisco.
Poster Title: Preliminary Results from Patients with Urothelial Carcinoma (UC) in a Phase 1A/1B study of BGB-A317, an Anti-PD-1 Monoclonal Antibody
Abstract: 445; Poster Board: G16
Presenter: Shahneen Sandhu, M.D.
Poster Session B: Prostate Cancer, Urothelial Carcinoma, and Penile, Urethral, and Testicular Cancers
Date & Times: Friday, February 9, 2018 at 12:15-1:45 PM (PT) and 6:00-7:00 PM (PT)
Location: Moscone West Building, San FranciscoAbout Tislelizumab (BGB-A317)
Tislelizumab is an investigational humanized monoclonal antibody that belongs to a class of immuno-oncology agents known as immune checkpoint inhibitors. It is designed to bind to PD-1, a cell surface receptor that plays an important role in downregulating the immune system by preventing the activation of T-cells. Tislelizumab has demonstrated high affinity and specificity for PD-1. It is differentiated from the currently approved PD-1 antibodies in an engineered Fc region, which is believed to minimize potentially negative interactions with other immune cells. Tislelizumab is being developed as a monotherapy and in combination with other therapies for the treatment of a broad array of both solid tumor and hematologic cancers. BeiGene and Celgene Corporation have a global strategic collaboration for tislelizumab for solid tumors outside of Asia (except Japan). About BeiGene
BeiGene is a global, commercial-stage, research-based biotechnology company focused on molecularly targeted and immuno-oncology cancer therapeutics. With a team of over 850 employees in China, the United States, and Australia, BeiGene is advancing a pipeline consisting of novel oral small molecules and monoclonal antibodies for cancer. BeiGene is also working to create combination solutions aimed to have both a meaningful and lasting impact on cancer patients. BeiGene markets ABRAXANEÂ® (nanoparticle albuminâ€“bound paclitaxel), REVLIMIDÂ® (lenalidomide), and VIDAZAÂ® (azacitidine) in China under a license from Celgene Corporation.iForward-Looking Statements
This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 and other federal securities laws, including statements regarding BeiGeneâ€™s advancement and anticipated clinical development of tislelizumab and its other drug candidates. Actual results may differ materially from those indicated in the forward-looking statements as a result of various important factors, including BeiGene's ability to demonstrate the efficacy and safety of its drug candidates; the clinical results for its drug candidates, which may not support further development; actions of regulatory agencies, which may affect the initiation, timing and progress of clinical trials; BeiGene's ability to achieve market acceptance in the medical community necessary for commercial success; BeiGene's ability to obtain and maintain protection of intellectual property for its technology and drugs; BeiGene's reliance on third parties to conduct drug development, manufacturing and other services; BeiGeneâ€™s limited operating history and BeiGene's ability to obtain additional funding for operations and to complete the development and commercialization of its drug candidates, as well as those risks more fully discussed in the section entitled â€œRisk Factorsâ€� in BeiGeneâ€™s most recent quarterly report on Form 10-Q, as well as discussions of potential risks, uncertainties, and other important factors in BeiGene's subsequent filings with the U.S. Securities and Exchange Commission. All information in this press release is as of the date of this press release, and BeiGene undertakes no duty to update such information unless required by law.
i ABRAXANEÂ®, REVLIMIDÂ®, and VIDAZAÂ® are registered trademarks of Celgene Corporation.Investor Contact
Lucy Li, Ph.D.
[email protected]Media Contact
+ 1 857-302-5663
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